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20 E 46th St, New York, NY, Class B Office Building

  • Upon Request
20 E 46th St #401, New York, NY 10017, USA
For Lease/Rent
20 E 46th St, New York, NY, Class B Office Building
20 E 46th St #401, New York, NY 10017, USA
  • Upon Request

Description

20 E 46th St, New York, NY, Class B Office Building

 

20 E 46th St, New York, NY, 10017

Cross Street: Madison Avenue

15 Story Class B Office Building, Multiple Floors Available

Nestled just steps from Grand Central Station, 20 East 46th Street is a prime destination for tenants seeking exceptional value and a vibrant work environment.

This building boasts a newly refurbished lobby that welcomes visitors with a modern touch, alongside upgraded elevator cabs and refreshed common corridors that enhance the overall aesthetic. With convenient common area restrooms, it’s designed for ease and functionality.

Offering 24/7 access, 20 East 46th Street is a full-service building equipped to meet the diverse needs of its tenants. A public parking facility conveniently located across the street adds to its accessibility.

Future renovations will introduce a chic new lobby and building entrance, cutting-edge elevators, upgraded AC chilling units for optimal comfort, and newly designed hallways featuring digital tenant signage on each floor. Renovated restrooms will also elevate the tenant experience.

Ideal for medical or dental practices, this building provides the perfect blend of location and amenities, ensuring a professional setting that caters to both staff and patients. With its strategic positioning and thoughtful upgrades, 20 East 46th Street is poised to be an attractive option for health-focused businesses looking to thrive in the heart of the city.

Grand Central Station office space average price for rent: Class B $60-70 per SF.

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Property Details

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  • Some space are fully built out with furniture
  • Some space just open floors
  • Total floors: 15
  • Total Building Size: 120,000 SF
  • Typical Floor Size: 4,566 SF
  • Available space on multiple floors for lease at affordable rates
  • Sizes from 1,152 SF – 6,856 SF up to 19,904 SF
  • Floors from 3rd and 11th
  • Year Built: 1958

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Building Amenities

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  • Bus Line
  • Metro/Subway

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Notable tenants at this location
  • Omni Eye Services
  • Sue Decotiis, MD
  • 20 East Medical
  • Galynker Family Center For Bipolar Disorder
  • Meridian Dental Group
  • Medical First New York P.C.
  • Nilesh Patel, MD
  • Midtown Dental
  • Dr. Gerard Varlotta, DO, FACSM
  • INVO Pain Medicine Group
  • Grand Central Physical Medicine & Rehabilitation
  • Sachar Dental NYC
  • Karen D. Ziselman DMD, LLC
  • Pomerantz Dermatology
  • East Side Medical Practice
  • Overseas Japanese Family Dental

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Transportation in Grand Central Station

In this region, Grand Central Terminal is a primary transportation hub. It serves Metro-North trains and the East Side 4, 5, and 6 local and express subway lines. Grand Central acts as a central core for transit in Midtown Manhattan, offering rail, subway, bus, taxi, and airport service all within steps of the Main Concourse. Grand Central Terminal main entrance is 89 E. 42nd Street (at Park Avenue), New York, NY 10017. It is accessible via the 4, 5, 6, 7, and S subway lines, the M101, M102, M103, M1, M2, M3, M4, Q32, and M42 buses and the Hudson, Harlem, and New Haven lines on Metro-North.

Grand Central–42nd Street"4" train"5" train"6" train"6" express train"7" train"7" express train​​42nd Street Shuttle

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Details

Updated on November 30, 2025 at 1:16 pm
  • Property ID: GC-100-568
  • Price: Upon Request
  • Property Size: 120000 Sq Ft
  • Year Built: 1958
  • Property Type: Office Space
  • Property Status: For Lease/Rent
  • Price: per square foot
  • Lease term: 3-10 Years
  • Suite/Floor: Total Floors 15
  • Pre-built offices: 1 - 100
  • Reception Area: Yes
  • Central HVAC: Yes
  • Available Furniture: Yes
  • Attended Lobby: Yes
  • Building Class: B
  • Address 20 E 46th St
  • City New York
  • State/county New York
  • Zip/Postal Code 10017
  • Area Grand Central

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