E 49th St, Plaza District, Medical Office Space For Lease 2,800 SF, $25 per SF $5,833 /month
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East 49th Street is a seven-story commercial property situated in the heart of Midtown Manhattan, between Madison Avenue and Park Avenue. Built in 1930, the building embodies the classic commercial architecture of early 20th-century Manhattan and continues to serve as a functional, well-positioned office destination.
The property spans approximately 16,224 square feet of building area on a 2,553 square foot lot, offering seven individual commercial units across its seven floors. Its central location places it in one of New York City’s most vibrant business districts, with a Walk Score of 97, reflecting outstanding pedestrian accessibility. Major transportation hubs such as the 47–50 Sts–Rockefeller Center and 51 St subway stations, along with multiple bus routes, provide excellent connectivity for tenants and visitors.
Over the decades, East 49th Street has maintained its role as a reliable commercial address, contributing to Midtown’s dense and dynamic office market. The building also houses Osteria Delbianco, a refined Italian restaurant offering an inviting atmosphere and sophisticated cuisine. Its prime location is just steps from iconic New York City landmarks including the Chrysler Building and Grand Central Terminal, enhancing its appeal for both business and leisure.
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Being within walking distance to iconic landmarks, shopping centers, dining, and entertainment options, Plaza District gives an array of accessible choices for transportation options. A variety of subway and bus stations served this hot-spot location and giving you an easy way to moving from one point to another. The M1, M2, M5, M7, and M57, and the 5th Avenue Station is located right at the beginning of Central Park on 59th Street.
Subway:
| Lexington Avenue/59th Street |
| 59th Street–Columbus Circle |
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