W 125th St, Uptown Manhattan, Fully Built Out Medical Space For Lease 1,850 SF
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West 125th Street is a mixed-use, six-story walk-up building located in the heart of Manhattanville, just steps from Columbia University’s new campus and along the bustling 125th Street commercial corridor. Originally built in 1901 and significantly renovated in the 1990s, this well-maintained property combines classic New York architecture with modernized infrastructure.
The building features approximately 47,000 square feet of space, with ground-floor commercial frontage and multiple residential units above. The available street-level retail unit, measuring approximately 1,800 square feet, is ideally suited for medical, dental, or professional office use, with a partial build-out already in place from a former healthcare tenant.
Positioned on a high-visibility stretch of West 125th Street, the property benefits from strong pedestrian traffic, excellent transit access—including the 1 train at Broadway and the A/B/C/D lines at 125th Street—and close proximity to Columbia University, City College, and Harlem’s growing business and cultural scene.
Zoned for mixed commercial and residential use, W 125th St offers a compelling opportunity for tenants seeking affordable, flexible space in one of Upper Manhattan’s most rapidly evolving neighborhoods.
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The location of Harlem determines it as a strong public transport hub. You get plenty of New York Metro lines – A, B, C, D and 1, 2, 3 trains have all stops across Harlem. You can also use 5 Bronx bus lines and plenty of Manhattan bus lines. On 125th Street there is a rail station of the Metro North Railroad, where you can get the 4, 5 and 6 trains and also get regional trains to other counties in the vicinity.
Trains:
| Lexington Avenue Line | green |
| Broadway–Seventh Avenue Line | red |
| Eighth Avenue Line | blue |
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