271 Madison Ave, New York, NY, Grand Central, Class B Office Building For Lease

271 Madison Ave, New York, NY, Grand Central, Class B Office Building For Lease

 271 Madison Ave, New York, NY, 10016

Cross Streets are: E 39th St and E 40th St

22 Story Class B Office Building

Multiple floors available for rent

271 Madison Avenue is a 22-story Class B office building in Manhattan’s Murray Hill, originally built in 1927. It combines old-world charm—such as high ceilings and operable windows on three sides—with modern efficiency. The building offers flexible, light-filled floor plates of around 5,700 sq ft, 24/7 access, and an attended lobby. Strategically located just a few blocks from Grand Central, it provides excellent transit connectivity.

In 2025 Grand Central Station office space average price for rent: Class B $45-70 per SF.

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Property Details

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• Some space are fully built out with furniture
• Some space just open floors
• Total floors: 22
• Total Building Size: 111,500 SF
• Typical Floor Size: 5,783 SF
• Available space on multiple floors for lease at affordable rates
• Sizes from 3,224 SF – 5,250 SF up to 24,453 SF
• Floors from 2nd to 17th
• Year Built: 1927

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Building Amenities

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• Bus Line
• Metro/Subway

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Notable tenants at this location

• National Jewish Health
• Taylor & Taylor
• Daughters Of The Cincinnati
• J.C. Dwight Management
• Cornerstone Management Systems, Inc.

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Transportation in Grand Central Station

In this region, Grand Central Terminal is a primary transportation hub. It serves Metro-North trains and the East Side 4, 5, and 6 local and express subway lines. Grand Central acts as a central core for transit in Midtown Manhattan, offering rail, subway, bus, taxi, and airport service all within steps of the Main Concourse. Grand Central Terminal main entrance is 89 E. 42nd Street (at Park Avenue), New York, NY 10017. It is accessible via the 4, 5, 6, 7, and S subway lines, the M101, M102, M103, M1, M2, M3, M4, Q32, and M42 buses and the Hudson, Harlem, and New Haven lines on Metro-North.

Grand Central–42nd Street

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